Delayed Puberty and Estrogen Resistance in a Woman with Estrogen Receptor α Variant
نویسندگان
چکیده
منابع مشابه
Estrogen receptor α polymorphism in boys with constitutional delay of growth and puberty
PURPOSE There were a lot of reports regarding associations of polymorphisms in the estrogen receptor α (ESR1). with many disorders. But, those with constitutional delay of growth and puberty (CDGP) are not known. Our aim is to find out any association between CDGP and ESR1. METHODS In a total of 27 subjects, we compared 7 CDGP patients with 20 healthy controls with their heights and sexual ma...
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Estrogen action is mediated through several types of receptors (ERs), such as ERα, ERβ and putative membrane ERs. Oxytocin receptor (OTR) and ER expression levels in the rat uterus are regulated by estrogen; however, which types of ERs are involved has not been elucidated. This study examined OTR, ERα and ERβ levels in ovariectomized rats treated with 17β-estradiol (E2), an ERα agonist (PPT), a...
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ژورنال
عنوان ژورنال: New England Journal of Medicine
سال: 2013
ISSN: 0028-4793,1533-4406
DOI: 10.1056/nejmoa1303611